TLR4/NF-κB-Responsive MicroRNAs and Their Potential Target Genes: A Mouse Model of Skeletal Muscle Ischemia-Reperfusion Injury

Background. The aim of this study was to profile TLR4/NF-κB-responsive microRNAs (miRNAs) and their potential target genes in the skeletal muscles of mice following ischemia-reperfusion injury. Methods. Thigh skeletal muscles of C57BL/6, Tlr4−/−, and NF-κB−/− mice isolated based on femoral artery pe...

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Main Authors: Johnson Chia-Shen Yang, Shao-Chun Wu, Cheng-Shyuan Rau, Yi-Chun Chen, Tsu-Hsiang Lu, Yi-Chan Wu, Siou-Ling Tzeng, Chia-Jung Wu, Ching-Hua Hsieh
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2015/410721