In-Vitro and In-Vivo Evaluation of Velpatasvir- Loaded Mesoporous Silica Scaffolds. A Prospective Carrier for Drug Bioavailability Enhancement

In-Vitro and In-Vivo Evaluation of Velpatasvir- Loaded Mesoporous Silica Scaffolds. A Prospective Carrier for Drug Bioavailability Enhancement

The limited aqueous solubility of many active pharmaceutical ingredients (APIs) is responsible for their poor performance and low drug levels in blood and at target sites. Various approaches have been adopted to tackle this issue. Most recently, mesoporous silica nanoparticles (MSN) have gained atte...

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Bibliographic Details
Main Authors: Yasir Mehmood, Ikram Ullah Khan, Yasser Shahzad, Rizwan Ullah Khan, Muhammad Shahid Iqbal, Haseeb Ahmad Khan, Ikrima Khalid, Abid Mehmood Yousaf, Syed Haroon Khalid, Sajid Asghar, Muhammad Asif, Talib Hussain, Shefaat Ullah Shah
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Pharmaceutics
Subjects:
velpatasvir
solubility
bioavailability
mesoporous silica nanoparticles
Online Access:https://www.mdpi.com/1999-4923/12/4/307

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https://www.mdpi.com/1999-4923/12/4/307

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