ASC-Mediated Inflammation and Pyroptosis Attenuates <i>Brucella abortus</i> Pathogenesis Following the Recognition of gDNA

ASC-Mediated Inflammation and Pyroptosis Attenuates <i>Brucella abortus</i> Pathogenesis Following the Recognition of gDNA

<i>Brucella abortus</i> is a zoonotic pathogen that causes brucellosis. Because of <i>Brucella’s</i> unique LPS layer and intracellular localization predominately within macrophages, it can often evade immune detection. However, pattern recognition receptors are capable of se...

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Bibliographic Details
Main Authors: Juselyn D. Tupik, Sheryl L. Coutermarsh-Ott, Angela H. Benton, Kellie A. King, Hanna D. Kiryluk, Clayton C. Caswell, Irving C. Allen
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Pathogens
Subjects:
brucellosis
canonical inflammasome
non-canonical inflammasome
NLR
pyroptosis
ASC
Online Access:https://www.mdpi.com/2076-0817/9/12/1008

Internet

https://www.mdpi.com/2076-0817/9/12/1008

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