A distinct tethering step is vital for vacuole membrane fusion

Past experiments with reconstituted proteoliposomes, employing assays that infer membrane fusion from fluorescent lipid dequenching, have suggested that vacuolar SNAREs alone suffice to catalyze membrane fusion in vitro. While we could replicate these results, we detected very little fusion with the...

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Bibliographic Details
Main Authors: Michael Zick, William T Wickner
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-09-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/03251