Tumor escape and progression of HER-2/neu negative breast cancer under immune pressure

<p>Abstract</p> <p>Background</p> <p>Emerging data from pre-clinical and clinical studies suggest that HER-2/neu-specific T cell responses could induce HER-2/neu antigen loss in the tumor cells. These data suggest that patients with HER-2/neu negative breast cancer migh...

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Bibliographic Details
Main Authors: Wang Xiang-Yang, Wang Ena, Graham Laura, Ascierto Maria-Libera, Grimes Margaret M, Idowu Michael O, Payne Kyle K, Kmieciak Maciej, Bear Harry D, Manjili Masoud H
Format: Article
Language:English
Published: BMC 2011-03-01
Series:Journal of Translational Medicine
Online Access:http://www.translational-medicine.com/content/9/1/35