Pre-clinical left ventricular myocardial remodeling in patients with Friedreich's ataxia: A cardiac MRI study.

<h4>Background</h4>Heart Failure (HF) is the most common cause of death in Friedreich's ataxia (FRDA), an inherited mitochondrial disease. Myocardial fibrosis and myocardial hypertrophy are well-documented autopsy features among FRDA patients with HF.<h4>Objectives</h4>T...

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Main Authors: Karen A G Takazaki, Thiago Quinaglia, Thiago D Venancio, Alberto R M Martinez, Ravi V Shah, Tomas G Neilan, Michael Jerosch-Herold, Otávio R Coelho-Filho, Marcondes C França
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0246633