Cross-Reactive Donor-Specific CD8+ Tregs Efficiently Prevent Transplant Rejection

Cross-Reactive Donor-Specific CD8+ Tregs Efficiently Prevent Transplant Rejection

Summary: To reduce the use of non-specific immunosuppressive drugs detrimental to transplant patient health, therapies in development aim to achieve antigen-specific tolerance by promoting antigen-specific regulatory T cells (Tregs). However, identification of the natural antigens recognized by Treg...

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Bibliographic Details
Main Authors: Elodie Picarda, Séverine Bézie, Lorena Usero, Jason Ossart, Marine Besnard, Hanim Halim, Klara Echasserieau, Claire Usal, Jamie Rossjohn, Karine Bernardeau, Stéphanie Gras, Carole Guillonneau
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719316298

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http://www.sciencedirect.com/science/article/pii/S2211124719316298

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