Pazopanib, Cabozantinib, and Vandetanib in the Treatment of Progressive Medullary Thyroid Cancer with a Special Focus on the Adverse Effects on Hypertension

Pazopanib, Cabozantinib, and Vandetanib in the Treatment of Progressive Medullary Thyroid Cancer with a Special Focus on the Adverse Effects on Hypertension

Medullary thyroid cancer (MTC) is a rare malignancy with a poor prognosis. First line therapy is surgery, which is the only curative method of the disease. However, in non-operable cases or with tumor progression and metastases, a systemic treatment is necessary. This form of cancer is often insensi...

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Bibliographic Details
Main Authors: Rikke Vilsbøll Milling, Daniela Grimm, Marcus Krüger, Jirka Grosse, Sascha Kopp, Johann Bauer, Manfred Infanger, Markus Wehland
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:International Journal of Molecular Sciences
Subjects:
medullary thyroid carcinoma
hypertension
VEGF
antiangiogenesis
tyrosine kinase inhibitors
Online Access:http://www.mdpi.com/1422-0067/19/10/3258

Internet

http://www.mdpi.com/1422-0067/19/10/3258

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