Co-expression networks in generation of induced pluripotent stem cells

Co-expression networks in generation of induced pluripotent stem cells

We developed an adenoviral vector, in which Yamanaka's four reprogramming factors (RFs) were controlled by individual CMV promoters in a single cassette (Ad-SOcMK). This permitted coordinated expression of RFs (SOX2, OCT3/4, c-MYC and KLF4) in a cell for a transient period of time, synchronizin...

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Bibliographic Details
Main Authors: Sharan Paul, Lance Pflieger, Warunee Dansithong, Karla P. Figueroa, Fuying Gao, Giovanni Coppola, Stefan M. Pulst
Format: Article
Language:English
Published: The Company of Biologists 2016-03-01
Series:Biology Open
Subjects:
Adenoviral delivery
Gene expression
Reprogramming
iPSC
Online Access:http://bio.biologists.org/content/5/3/300

Internet

http://bio.biologists.org/content/5/3/300

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