Stimulation of airway and intestinal mucosal secretion by natural coumarin CFTR activators

Stimulation of airway and intestinal mucosal secretion by natural coumarin CFTR activators

Mutations of cystic fibrosis transmembrane conductance regulator (CFTR) cause lethal hereditary disease cystic fibrosis (CF) that involves extensive destruction and dysfunction of serous epithelium. Possible pharmacological therapy includes correction of defective intracellular processing and abnorm...

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Bibliographic Details
Main Authors: Hong eYang, Lina eXu, Yujie eSui, Xin eLiu, Chengyan eHe, Rouyu eFang, Jia eLiu, Feng eHao, Tong-Hui eMa
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-09-01
Series:Frontiers in Pharmacology
Subjects:
Colon
Coumarins
airway
CFTR
Mucosa
activator
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2011.00052/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphar.2011.00052/full

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