Hepatoprotective Effects of Silymarin on Liver Injury via Irisin Upregulation and Oxidative Stress Reduction in Rats with Type 2 Diabetes

Hepatoprotective Effects of Silymarin on Liver Injury via Irisin Upregulation and Oxidative Stress Reduction in Rats with Type 2 Diabetes

Background: Diabetes is one of the most prevalent metabolic diseases. Irisin (FNDC5 protein) is involved in the new strategy of combating type 2 diabetes. In the liver, the antidiabetic mechanism of silymarin at the molecular level is unknown. This study investigated the effects of silymarin on iris...

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Bibliographic Details
Main Authors: Nejat Kheiripour, Jamshid Karimi, Iraj Khodadadi, Heidar Tavilani, Mohammad Taghi Goodarzi, Mohammad Hashemnia
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2019-03-01
Series:Iranian Journal of Medical Sciences
Subjects:
Silymarin
FNDC5 protein
Diabetes mellitus type 2
Rat
Online Access:http://ijms.sums.ac.ir/article_44511_5e512216578ac4bdc28c7c383479976a.pdf

Internet

http://ijms.sums.ac.ir/article_44511_5e512216578ac4bdc28c7c383479976a.pdf

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