Successful infection of BALB/c mice by a swine hepatitis E virus clone constructed with reverse genetics

Abstract Background Hepatitis E virus (HEV) is a leading cause of hepatitis worldwide. However, its infection biology and pathogenesis remain largely elusive. Furthermore, no proven medication is available for treating hepatitis E. Robust experimental models are urgently required to advance the rese...

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Bibliographic Details
Main Authors: Wenhai Yu, Chenchen Yang, Xianhui Hao, Tianwu Ma, Fen Huang
Format: Article
Language:English
Published: BMC 2018-12-01
Series:BMC Infectious Diseases
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12879-018-3544-4