Fluoxetine and Ketamine Reverse the Depressive but Not Anxiety Behavior Induced by Lesion of Cholinergic Neurons in the Horizontal Limb of the Diagonal Band of Broca in Male Rat

Fluoxetine and Ketamine Reverse the Depressive but Not Anxiety Behavior Induced by Lesion of Cholinergic Neurons in the Horizontal Limb of the Diagonal Band of Broca in Male Rat

The basal forebrain cholinergic system is involved in cognitive processes, but the role of the basal forebrain cholinergic system in depression is unknown. We investigated whether a lesion of cholinergic neurons in the horizontal limb of the diagonal band of Broca (HDB) produces depressive-like beha...

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Bibliographic Details
Main Authors: Linghong Chen, Yuting Ke, Hong Ma, Lei Gao, Yiying Zhou, Huaqiang Zhu, Huifen Liu, Fuqiang Zhang, Wenhua Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
antidepressants
SSRI
choline acetyltransferase
rodent
ketamine
cholinergic neuron
Online Access:https://www.frontiersin.org/articles/10.3389/fnbeh.2021.602708/full

Internet

https://www.frontiersin.org/articles/10.3389/fnbeh.2021.602708/full

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