Brain-enriched microRNAs circulating in plasma as novel biomarkers for Rett syndrome.

Rett syndrome (RTT) is a severe neurodevelopmental disorder caused by mutations in the X-linked gene MECP2 (methyl-CpG-binding protein 2). Minimally invasive and accurate biomarkers of disease progression and treatment response could facilitate screening of therapeutic compounds in animal models, en...

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Bibliographic Details
Main Authors: Kira Sheinerman, Aleksandra Djukic, Vladimir G Tsivinsky, Samuil R Umansky
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0218623