Inhibition of Microglial TGFβ Signaling Increases Expression of Mrc1

Microglia are constantly surveying their microenvironment and rapidly react to impairments by changing their morphology, migrating toward stimuli and adopting gene expression profiles characterizing their activated state. The increased expression of the M2-like marker Mannose receptor 1 (Mrc1), whic...

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Bibliographic Details
Main Authors: Alexander von Ehr, Abdelraheim Attaai, Nicolas Neidert, Phani Sankar Potru, Tamara Ruß, Tanja Zöller, Björn Spittau
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2020.00066/full