Establishment and evaluation of a PRRSV-sensitive porcine endometrial epithelial cell line by transfecting SV40 large T antigen

Establishment and evaluation of a PRRSV-sensitive porcine endometrial epithelial cell line by transfecting SV40 large T antigen

Abstract Background PRRSV is an infectious illness causing lung injury and abortion in sows. Cells apoptosis in the interface between the endometrium and fetal placenta is a crucial factor causing abortion. Previous study confirmed PRRSV could cause apoptosis of macrophages but rarely produced an ob...

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Bibliographic Details
Main Authors: Kang Zhang, Houshen Li, Shasha Dong, Ying Liu, Dong Wang, Haichang Liu, Feng Su, Lijiang Ge, Yunliang Jiang
Format: Article
Language:English
Published: BMC 2019-08-01
Series:BMC Veterinary Research
Subjects:
Porcine endometrial epithelial cell line
SV40T antigen
PRRSV-sensitivity
Lentrival vector
Replication efficiency
Online Access:http://link.springer.com/article/10.1186/s12917-019-2051-1

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http://link.springer.com/article/10.1186/s12917-019-2051-1

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