Clinical Practice Use of Liquid Biopsy to Identify <i>RAS</i>/<i>BRAF</i> Mutations in Patients with Metastatic Colorectal Cancer (mCRC): A Single Institution Experience

Clinical Practice Use of Liquid Biopsy to Identify <i>RAS</i>/<i>BRAF</i> Mutations in Patients with Metastatic Colorectal Cancer (mCRC): A Single Institution Experience

Tumor heterogeneity represents a possible cause of error in detecting predictive genetic alterations on tumor tissue and can be overcome by testing alterations in circulating tumor DNA (ctDNA) using liquid biopsy. We assessed 72 consecutive patients with a diagnosis of metastatic colorectal cancer (...

Full description

Bibliographic Details
Main Authors: Pietro Paolo Vitiello, Vincenzo De Falco, Emilio Francesco Giunta, Davide Ciardiello, Claudia Cardone, Pasquale Vitale, Nicoletta Zanaletti, Carola Borrelli, Luca Poliero, Marinella Terminiello, Gianluca Arrichiello, Vincenza Caputo, Vincenzo Famiglietti, Valentina Mattera Iacono, Francesca Marrone, Alessandra Di Liello, Giulia Martini, Stefania Napolitano, Michele Caraglia, Angela Lombardi, Renato Franco, Ferdinando De Vita, Floriana Morgillo, Teresa Troiani, Fortunato Ciardiello, Erika Martinelli
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Cancers
Subjects:
colorectal cancer
liquid biopsy
<i>ras</i> testing
anti-egfr
acquired resistance
clonal evolution
Online Access:https://www.mdpi.com/2072-6694/11/10/1504

Internet

https://www.mdpi.com/2072-6694/11/10/1504

Similar Items