Vesicular trafficking to the immune synapse: how to assemble receptor-tailored pathways from a basic building set
The signals that orchestrate T-cell activation are coordinated within a highly organized interface with the antigen presenting cell (APC), known as the immune synapse (IS). IS assembly depends on T-cell antigen receptor (TCR) engagement by a specific peptide antigen-major histocompatibility complex...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2016-02-01
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| Series: | Frontiers in Immunology |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00050/full |