Insulin signaling and dietary restriction differentially influence the decline of learning and memory with age.

Of all the age-related declines, memory loss is one of the most devastating. While conditions that increase longevity have been identified, the effects of these longevity-promoting factors on learning and memory are unknown. Here we show that the C. elegans Insulin/IGF-1 receptor mutant daf-2 improv...

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Bibliographic Details
Main Authors: Amanda L Kauffman, Jasmine M Ashraf, M Ryan Corces-Zimmerman, Jessica N Landis, Coleen T Murphy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-05-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC2872642?pdf=render