Decoy Receptor Interactions as Novel Drug Targets against EKC-Causing Human Adenovirus

Decoy Receptor Interactions as Novel Drug Targets against EKC-Causing Human Adenovirus

Epidemic keratoconjunctivitis (EKC) is a severe ocular disease and can lead to visual impairment. Human adenovirus type-37 (HAdV-D37) is one of the major causative agents of EKC and uses sialic acid (SA)-containing glycans as cellular receptors. Currently, there are no approved antivirals available...

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Bibliographic Details
Main Authors: Naresh Chandra, Lars Frängsmyr, Niklas Arnberg
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Viruses
Subjects:
glycosaminoglycans
adenovirus
cellular receptor
decoy receptor
epidemic keratoconjunctivitis
GAG-mimetic
Online Access:http://www.mdpi.com/1999-4915/11/3/242

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http://www.mdpi.com/1999-4915/11/3/242

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