Morphological Changes of Human Corneal Endothelial Cells after Rho-Associated Kinase Inhibitor Eye Drop (Ripasudil) Administration: A Prospective Open-Label Clinical Study.

To investigate the effect and safety of a selective Rho kinase inhibitor, ripasudil 0.4% eye drops, on corneal endothelial cells of healthy subjects.Prospective, interventional case series.In this study, 6 healthy subjects were administered ripasudil 0.4% in the right eye twice daily for 1 week. Mor...

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Bibliographic Details
Main Authors: Hiroko Nakagawa, Noriko Koizumi, Naoki Okumura, Hideki Suganami, Shigeru Kinoshita
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4569567?pdf=render