Inducible Nitric Oxide Regulates Brush Border Membrane Na-Glucose Co-transport, but Not Na:H Exchange via p38 MAP Kinase in Intestinal Epithelial Cells

Inducible Nitric Oxide Regulates Brush Border Membrane Na-Glucose Co-transport, but Not Na:H Exchange via p38 MAP Kinase in Intestinal Epithelial Cells

During chronic intestinal inflammation in rabbit intestinal villus cells brush border membrane (BBM) Na-glucose co-transport (SGLT1), but not Na/H exchange (NHE3) is inhibited. The mechanism of inhibition is secondary to a decrease in the number of BBM co-transporters. In the chronic enteritis mucos...

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Bibliographic Details
Main Authors: Palanikumar Manoharan, Shanmuga Sundaram, Soudamani Singh, Uma Sundaram
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:Cells
Subjects:
peroxynitrite
SGLT1
p38 MAPK
chronic intestinal inflammation
Online Access:http://www.mdpi.com/2073-4409/7/8/111

Internet

http://www.mdpi.com/2073-4409/7/8/111

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