The E3 ubiquitin ligase TRIM25 regulates adipocyte differentiation via proteasome-mediated degradation of PPARγ
Metabolic disorders: TRIM-ming the fat A protein that targets peroxisome proliferator-activated receptor γ (PPARγ) (a key regulator of fat cell formation) for degradation suppresses the formation of fat. Excess fat can lead to obesity and cause type 2 diabetes and cardiovascular disease, yet little...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2018-10-01
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| Series: | Experimental and Molecular Medicine |
| Online Access: | https://doi.org/10.1038/s12276-018-0162-6 |