Characterization of Aneuploid Populations with Trisomy 7 and 20 Derived from Diploid Human Colonic Epithelial Cells

Chromosomal instability leading to aneuploidy occurs in most sporadic colorectal cancers (CRCs) and is believed to be an early driving force in disease progression. Despite this observation, the cellular advantages conferred by these cytogenetic alterations are poorly understood. Here, we provide e...

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Bibliographic Details
Main Authors: Peter Ly, Ugur Eskiocak, Sang B. Kim, Andres I. Roig, Suzie K. Hight, Dypti R. Lulla, Ying S. Zou, Kimberly Batten, Woodring E. Wright, Jerry W. Shay
Format: Article
Language:English
Published: Elsevier 2011-04-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558611800163