Parasite load induces progressive spleen architecture breakage and impairs cytokine mRNA expression in Leishmania infantum-naturally infected dogs.

Parasite load induces progressive spleen architecture breakage and impairs cytokine mRNA expression in Leishmania infantum-naturally infected dogs.

Canine Visceral Leishmaniasis (CVL) shares many aspects with the human disease and dogs are considered the main urban reservoir of L. infantum in zoonotic VL. Infected dogs develop progressive disease with a large clinical spectrum. A complex balance between the parasite and the genetic/immunologica...

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Bibliographic Details
Main Authors: Amanda S Cavalcanti, Marcelo Ribeiro-Alves, Luiza de O R Pereira, Gustavo Leandro Mestre, Anna Beatriz Robottom Ferreira, Fernanda N Morgado, Mariana C Boité, Elisa Cupolillo, Milton O Moraes, Renato Porrozzi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4395300?pdf=render

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http://europepmc.org/articles/PMC4395300?pdf=render

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