Changes in Posttraumatic Brain Edema in Craniectomy-Selective Brain Hypothermia Model Are Associated With Modulation of Aquaporin-4 Level

Changes in Posttraumatic Brain Edema in Craniectomy-Selective Brain Hypothermia Model Are Associated With Modulation of Aquaporin-4 Level

Both hypothermia and decompressive craniectomy have been considered as a treatment for traumatic brain injury. In previous experiments we established a murine model of decompressive craniectomy and we presented attenuated edema formation due to focal brain cooling. Since edema development is regulat...

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Bibliographic Details
Main Authors: Jacek Szczygielski, Cosmin Glameanu, Andreas Müller, Markus Klotz, Christoph Sippl, Vanessa Hubertus, Karl-Herbert Schäfer, Angelika E. Mautes, Karsten Schwerdtfeger, Joachim Oertel
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Neurology
Subjects:
traumatic brain injury
decompressive craniectomy
brain edema
hypothermia
aquaporin-4
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2018.00799/full

Internet

https://www.frontiersin.org/article/10.3389/fneur.2018.00799/full

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