Fish Granzyme A Shows a Greater Role Than Granzyme B in Fish Innate Cell-Mediated Cytotoxicity

Fish Granzyme A Shows a Greater Role Than Granzyme B in Fish Innate Cell-Mediated Cytotoxicity

Granzymes (Gzm) are serine proteases, contained into the secretory granules of cytotoxic cells, responsible for the cell-mediated cytotoxicity (CMC) against tumor cells and intracellular pathogens such as virus and bacteria. In fish, they have received little attention to their existence, classifica...

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Bibliographic Details
Main Authors: Elena Chaves-Pozo, Yulema Valero, Maria Teresa Lozano, Pablo Rodríguez-Cerezo, Liang Miao, Vittorio Campo, Maria Angeles Esteban, Alberto Cuesta
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Immunology
Subjects:
granzymes
cell-mediated cytotoxicity
granzyme A
granzyme B
nodavirus
fish
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02579/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02579/full

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