Influence of crystal habit on the dissolution of simvastatin single crystals

In order to achieve better in-vivo performance of the final dosage form comprising a poorly soluble drug the physicochemical properties of the active pharmaceutical ingredient can be altered not only by changing the solid state form but also through the conversion of their crystal habits. To elucida...

Full description

Bibliographic Details
Main Authors: Polona Bukovec, Anton Meden, Matej Smrkolj, Franc Vrečer
Format: Article
Language:English
Published: Slovenian Chemical Society 2015-11-01
Series:Acta Chimica Slovenica
Subjects:
Online Access:https://journals.matheo.si/index.php/ACSi/article/view/1849