Comparative proteomic analysis of differentially expressed proteins in the urine of reservoir hosts of leptospirosis.

Rattus norvegicus is a natural reservoir host for pathogenic species of Leptospira. Experimentally infected rats remain clinically normal, yet persistently excrete large numbers of leptospires from colonized renal tubules via urine, despite a specific host immune response. Whilst persistent renal co...

Full description

Bibliographic Details
Main Authors: Jarlath E Nally, Avril M Monahan, Ian S Miller, Ruben Bonilla-Santiago, Puneet Souda, Julian P Whitelegge
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3197145?pdf=render