Ackr3-Venus knock-in mouse lights up brain vasculature

Ackr3-Venus knock-in mouse lights up brain vasculature

Abstract The atypical chemokine receptor 3, ACKR3, is a G protein-coupled receptor, which does not couple to G proteins but recruits βarrestins. At present, ACKR3 is considered a target for cancer and cardiovascular disorders, but less is known about the potential of ACKR3 as a target for brain dise...

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Bibliographic Details
Main Authors: Aliza T. Ehrlich, Meriem Semache, Pierre Couvineau, Stefan Wojcik, Hiroyuki Kobayashi, Marcus Thelen, Florence Gross, Mireille Hogue, Christian Le Gouill, Emmanuel Darcq, Michel Bouvier, Brigitte L. Kieffer
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Molecular Brain
Subjects:
CXCR7
GPCR
Signaling
G protein
βarrestin
GABA
Online Access:https://doi.org/10.1186/s13041-021-00862-y

Internet

https://doi.org/10.1186/s13041-021-00862-y

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