Methanol extract of Dicranopteris linearis L. leaves impedes acetaminophen-induced liver intoxication partly by enhancing the endogenous antioxidant system

Methanol extract of Dicranopteris linearis L. leaves impedes acetaminophen-induced liver intoxication partly by enhancing the endogenous antioxidant system

Abstract Background The present study investigated the potential of methanolic extract of Dicranopteris linearis (MEDL) leaves to attenuate liver intoxication induced by acetaminophen (APAP) in rats. Methods A group of mice (n = 5) treated orally with a single dose (5000 mg/kg) of MEDL was first sub...

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Bibliographic Details
Main Authors: Zainul Amiruddin Zakaria, Farah Hidayah Kamisan, Maizatul Hasyima Omar, Nur Diyana Mahmood, Fezah Othman, Siti Selina Abdul Hamid, Muhammad Nazrul Hakim Abdullah
Format: Article
Language:English
Published: BMC 2017-05-01
Series:BMC Complementary and Alternative Medicine
Subjects:
Dicranopteris linearis
Gleicheniaceae
Methanol extract
Hepatoprotection
Volatile compounds
Online Access:http://link.springer.com/article/10.1186/s12906-017-1781-5

Internet

http://link.springer.com/article/10.1186/s12906-017-1781-5

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