Intermittent fasting alleviates the neuropathic phenotype in a mouse model of Charcot–Marie–Tooth disease

Intermittent fasting alleviates the neuropathic phenotype in a mouse model of Charcot–Marie–Tooth disease

Charcot–Marie–Tooth type 1A (CMT1A) neuropathies linked to the misexpression of peripheral myelin protein 22 (PMP22) are progressive demyelinating disorders of the peripheral nervous system. In this study we asked whether dietary restriction by intermittent fasting (IF) could alleviate the neuropath...

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Bibliographic Details
Main Authors: Irina Madorsky, Katherine Opalach, Amanda Waber, Jonathan D. Verrier, Chelsea Solmo, Thomas Foster, William A. Dunn, Jr., Lucia Notterpek
Format: Article
Language:English
Published: Elsevier 2009-04-01
Series:Neurobiology of Disease
Subjects:
Neuropathy
Myelin
Dietary regimen
Autophagy
Chaperones
Schwann cells
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996109000047

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http://www.sciencedirect.com/science/article/pii/S0969996109000047

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