Selective Inactivation of Fibroblast Growth Factor 22 (FGF22) in CA3 Pyramidal Neurons Impairs Local Synaptogenesis and Affective Behavior Without Affecting Dentate Neurogenesis

Various growth factors regulate synapse development and neurogenesis, and are essential for brain function. Changes in growth factor signaling are implicated in many neuropsychiatric disorders such as depression, autism and epilepsy. We have previously identified that fibroblast growth factor 22 (FG...

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Bibliographic Details
Main Authors: Akiko Terauchi, Elizabeth Gavin, Julia Wilson, Hisashi Umemori
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-12-01
Series:Frontiers in Synaptic Neuroscience
Subjects:
CA3
Online Access:http://journal.frontiersin.org/article/10.3389/fnsyn.2017.00017/full