Optimal Antibody Purification Strategies Using Data-Driven Models
This work addresses the multiscale optimization of the purification processes of antibody fragments. Chromatography decisions in the manufacturing processes are optimized, including the number of chromatography columns and their sizes, the number of cycles per batch, and the operational flow velocit...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2019-12-01
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| Series: | Engineering |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2095809919308616 |