Correlation between resistance to trastuzumab and miR-141 relative expression in the BT-474 human breast cancer cell line

Background and Aim: Resistance to trastuzumab has been a critical barrier to targeted therapy of HER 2-positive (Human Epidermal Growth Factor Receptor 2) breast cancers. MicroRNAs (miRNAs) are known as decisive core regulators of drug resistance that modulate the epithelial-to-mesenchymal transitio...

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Bibliographic Details
Main Authors: Zohreh Rezaei, Dor Mohammad Kordi-Tamandani, Ahmadreza Sebzari, Kazem Dastjerdi
Format: Article
Language:fas
Published: Birjand University of Medical Sciences and Health Services 2017-10-01
Series:Journal of Birjand University of Medical Sciences
Subjects:
Online Access:http://journal.bums.ac.ir/browse.php?a_code=A-10-1232-1&slc_lang=en&sid=1