Indirect regulation of HMGB1 release by gasdermin D

HMGB1 is an inflammatory mediator released by a variety of cell types. Here, the authors show that unlike IL-1β, HMGB1 is released non-specifically following cell lysis.

Bibliographic Details
Main Authors: Allen Volchuk, Anna Ye, Leon Chi, Benjamin E. Steinberg, Neil M. Goldenberg
Format: Article
Language:English
Published: Nature Publishing Group 2020-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-18443-3