Mesenchymal Stem/Stromal Cell-Derived Extracellular Vesicles Elicit Better Preservation of the Intra-Renal Microvasculature Than Renal Revascularization in Pigs with Renovascular Disease

Mesenchymal Stem/Stromal Cell-Derived Extracellular Vesicles Elicit Better Preservation of the Intra-Renal Microvasculature Than Renal Revascularization in Pigs with Renovascular Disease

Background: Percutaneous transluminal renal angioplasty (PTRA) confers clinical and mortality benefits in select ‘high-risk’ patients with renovascular disease (RVD). Intra-renal-delivered extracellular vesicles (EVs) released from mesenchymal stem/stromal cells (MSCs) protect the kidney in experime...

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Bibliographic Details
Main Authors: Christopher M. Ferguson, Rahele A. Farahani, Xiang-Yang Zhu, Hui Tang, Kyra L. Jordan, Ishran M. Saadiq, Amir Lerman, Lilach O. Lerman, Alfonso Eirin
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cells
Subjects:
renovascular disease
microvasculature
revascularization
mesenchymal stem/stromal cells
extracellular vesicles
Online Access:https://www.mdpi.com/2073-4409/10/4/763

Internet

https://www.mdpi.com/2073-4409/10/4/763

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