Extracellular histones in lung dysfunction: a new biomarker and therapeutic target?
Extracellular histones released from injured or dying cells following trauma and other severe insults can act as potent damage-associated molecular patterns. In fact, elevated levels of histones are present in human circulation in hyperinflammatory states such as acute respiratory distress syndrome...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2020-11-01
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Series: | Pulmonary Circulation |
Online Access: | https://doi.org/10.1177/2045894020965357 |