Extracellular histones in lung dysfunction: a new biomarker and therapeutic target?

Extracellular histones released from injured or dying cells following trauma and other severe insults can act as potent damage-associated molecular patterns. In fact, elevated levels of histones are present in human circulation in hyperinflammatory states such as acute respiratory distress syndrome...

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Bibliographic Details
Main Authors: Pratap Karki, Konstantin G. Birukov, Anna A. Birukova
Format: Article
Language:English
Published: SAGE Publishing 2020-11-01
Series:Pulmonary Circulation
Online Access:https://doi.org/10.1177/2045894020965357