Dynamical Behavior and Conformational Selection Mechanism of the Intrinsically Disordered Sic1 Kinase-Inhibitor Domain

Intrinsically Disordered Peptides and Proteins (IDPs) in solution can span a broad range of conformations that often are hard to characterize by both experimental and computational methods. However, obtaining a significant representation of the conformational space is important to understand mechani...

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Bibliographic Details
Main Authors: Davide Sala, Ugo Cosentino, Anna Ranaudo, Claudio Greco, Giorgio Moro
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Life
Subjects:
Online Access:https://www.mdpi.com/2075-1729/10/7/110