Design of DOX-GNRs-PNIPAM@PEG-PLA Micelle With Temperature and Light Dual-Function for Potent Melanoma Therapy

Design of DOX-GNRs-PNIPAM@PEG-PLA Micelle With Temperature and Light Dual-Function for Potent Melanoma Therapy

Objective: The aim of this study was to construct light and temperature dual-sensitive micellar carriers loaded with doxorubicin (DOX) and gold nanorods (DOX-GNRs-PNIPAM@PEG-PLA, DAPP) for melanoma therapy.Methods: The DAPP self-assembled using fine-tuned physicochemical properties in water. The DAP...

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Bibliographic Details
Main Authors: Na Wang, Jing Shi, Cong Wu, Weiwei Chu, Wanru Tao, Wei Li, Xiaohai Yuan
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Chemistry
Subjects:
doxorubicin
gold nanorods
thermosensitive
photothermal therapy
melanoma
B16F10
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2020.599740/full

Internet

https://www.frontiersin.org/articles/10.3389/fchem.2020.599740/full

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