The endoplasmic reticulum chaperone GRP170: from immunobiology to cancer therapeutic

The endoplasmic reticulum chaperone GRP170: from immunobiology to cancer therapeutic

Glucose-regulated protein 170 (GRP170) is the largest member of GRP family that resides in the endoplasmic reticulum (ER). As a component of the ER chaperone network, GRP170 assists in protein folding, assembly, and transportation of secretory or transmembrane proteins. The well documented cytoprote...

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Bibliographic Details
Main Authors: Hongxia eWang, Abdul ePezeshki, Xiaofei eYu, Chunqing eGuo, John R Subjeck, Xiang-Yang eWang
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-01-01
Series:Frontiers in Oncology
Subjects:
Endoplasmic Reticulum
cancer vaccine
antigen cross-presentation
molecular chaperone
antitumor immunity
glucose-regulated protein
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2014.00377/full

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http://journal.frontiersin.org/Journal/10.3389/fonc.2014.00377/full

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