Characterization of glycolytic enzymes--rAldolase and rEnolase of Leishmania donovani, identified as Th1 stimulatory proteins, for their immunogenicity and immunoprophylactic efficacies against experimental visceral leishmaniasis.

Characterization of glycolytic enzymes--rAldolase and rEnolase of Leishmania donovani, identified as Th1 stimulatory proteins, for their immunogenicity and immunoprophylactic efficacies against experimental visceral leishmaniasis.

Th1 immune responses play an important role in controlling Visceral Leishmaniasis (VL) hence, Leishmania proteins stimulating T-cell responses in host, are thought to be good vaccine targets. Search of such antigens eliciting cellular responses in Peripheral blood mononuclear cells (PBMCs) from cure...

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Bibliographic Details
Main Authors: Reema Gupta, Vikash Kumar, Pramod Kumar Kushawaha, Chandradev Pati Tripathi, Sumit Joshi, Amogh Anant Sahasrabuddhe, Kalyan Mitra, Shyam Sundar, Mohammad Imran Siddiqi, Anuradha Dube
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3901665?pdf=render

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http://europepmc.org/articles/PMC3901665?pdf=render

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