Accumulation of cholesterol precursors and plant sterols in human stenotic aortic valves

Accumulation of cholesterol precursors and plant sterols in human stenotic aortic valves

The pathogenesis of aortic valve stenosis (AS) is characterized by the accumulation of LDL-derived cholesterol in the diseased valves. Since LDL particles also contain plant sterols, we investigated whether plant sterols accumulate in aortic valve lesions. Serum samples were collected from 82 patien...

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Bibliographic Details
Main Authors: Satu Helske, Tatu Miettinen, Helena Gylling, Mikko Mäyränpää, Jyri Lommi, Heikki Turto, Kalervo Werkkala, Markku Kupari, Petri T. Kovanen
Format: Article
Language:English
Published: Elsevier 2008-07-01
Series:Journal of Lipid Research
Subjects:
aortic stenosis
noncholesterol sterols
phytosterols
absorption
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520347222

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http://www.sciencedirect.com/science/article/pii/S0022227520347222

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