Fluoride exposure during pregnancy and lactation triggers oxidative stress and molecular changes in hippocampus of offspring rats

Fluoride exposure during pregnancy and lactation triggers oxidative stress and molecular changes in hippocampus of offspring rats

Long-term exposure to high concentrations of fluoride (F) can damage mineralized and soft tissues such as bones, liver, kidney, intestine, and nervous system of adult rats. The high permeability of the blood–brain barrier and placenta to F during pregnancy and lactation may be critical to neurologic...

Full description

Bibliographic Details
Main Authors: Maria Karolina Martins Ferreira, Walessa Alana Bragança Aragão, Leonardo Oliveira Bittencourt, Bruna Puty, Aline Dionizio, Michel Platini Caldas de Souza, Marilia Afonso Rabelo Buzalaf, Edivaldo Herculano de Oliveira, Maria Elena Crespo-Lopez, Rafael Rodrigues Lima
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Fluoride
Offspring
Neurotoxicity
Oxidative stress
BDNF
Proteomic
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651320312744

Internet

http://www.sciencedirect.com/science/article/pii/S0147651320312744

Similar Items