Subnanometre-resolution structure of the doublet microtubule reveals new classes of microtubule-associated proteins

Cilia are hair-like appendages involved in cell motility and sensory reception. Here, the authors report a high resolution cryo-EM structure of the microtubule doublet from motile cilia and identify microtubule inner proteins (MIPs) bound to the inner surface of the doublet that appear to stabilize...

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Bibliographic Details
Main Authors: Muneyoshi Ichikawa, Dinan Liu, Panagiotis L. Kastritis, Kaustuv Basu, Tzu Chin Hsu, Shunkai Yang, Khanh Huy Bui
Format: Article
Language:English
Published: Nature Publishing Group 2017-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms15035