Phenformin as an Anticancer Agent: Challenges and Prospects

Phenformin as an Anticancer Agent: Challenges and Prospects

Currently, there is increasing evidence linking diabetes mellitus (especially type 2 diabetes mellitus) with carcinogenesis through various biological processes, such as fat-induced chronic inflammation, hyperglycemia, hyperinsulinemia, and angiogenesis. Chemotherapeutic agents are used in the treat...

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Bibliographic Details
Main Authors: Mª Eugenia García Rubiño, Esmeralda Carrillo, Gloria Ruiz Alcalá, Alicia Domínguez-Martín, Juan A. Marchal, Houria Boulaiz
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:International Journal of Molecular Sciences
Subjects:
biguanides
phenformin
cancer
diabetes type 2
cancer stem cells
Online Access:https://www.mdpi.com/1422-0067/20/13/3316

Internet

https://www.mdpi.com/1422-0067/20/13/3316

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