Hydrophilic Polyhedral Oligomeric Silsesquioxane, POSS(OH)<sub>32</sub>, as a Complexing Nanocarrier for Doxorubicin and Daunorubicin

Hydrophilic Polyhedral Oligomeric Silsesquioxane, POSS(OH)<sub>32</sub>, as a Complexing Nanocarrier for Doxorubicin and Daunorubicin

A novel strategy, recently developed by us, to use polyhedral oligomeric silsesquioxanes (POSS) as an anti-cancer drug carrier is presented. Anthracycline:POSS complexes were prepared by simple co-addition of doxorubicin (DOX) or daunorubicin (DAU) with hydrophilic POSS(OH)<sub>32</sub>....

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Bibliographic Details
Main Authors: Kinga Piorecka, Anna Janaszewska, Marta Majkowska, Monika Marcinkowska, Jan Kurjata, Slawomir Kazmierski, Ewa Radzikowska-Cieciura, Bartlomiej Kost, Przemyslaw Sowinski, Barbara Klajnert-Maculewicz, Wlodzimierz A. Stanczyk
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Materials
Subjects:
anti-cancer complexes
non-covalent systems
polyhedral oligomeric silsesquioxanes
anthracyclines
in vitro viability studies
Online Access:https://www.mdpi.com/1996-1944/13/23/5512

Internet

https://www.mdpi.com/1996-1944/13/23/5512

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