Immune-Mediated Mechanisms in Cofactor-Dependent Food Allergy and Anaphylaxis: Effect of Cofactors in Basophils and Mast Cells

Cofactors may explain why in some cases food ingestion leads to anaphylaxis while in others elicits a milder reaction or tolerance. With cofactors, reactions become more severe and/or have a lower allergen threshold. Cofactors are present in up to 58% of food anaphylaxis (FAn). Exercise, NSAIDs, and...

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Main Authors: Rosa Muñoz-Cano, Clara San Bartolome, Rocío Casas-Saucedo, Giovanna Araujo, Sonia Gelis, Maria Ruano-Zaragoza, Jordi Roca-Ferrer, Francis Palomares, Margarita Martin, Joan Bartra, Mariona Pascal
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.623071/full