The c-Myc-regulated lncRNA NEAT1 and paraspeckles modulate imatinib-induced apoptosis in CML cells

The c-Myc-regulated lncRNA NEAT1 and paraspeckles modulate imatinib-induced apoptosis in CML cells

Abstract Chronic myeloid leukemia (CML) is a clonal disease characterized by the presence of the constitutively active tyrosine kinase BCR-ABL oncoprotein. Although BCR-ABL is crucially important for pathogenesis and treatment response, it is thought that some additional factors might be involved in...

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Bibliographic Details
Main Authors: Chengwu Zeng, Sichu Liu, Shuai Lu, Xibao Yu, Jing Lai, Yifan Wu, Shaohua Chen, Liang Wang, Zhi Yu, Gengxin Luo, Yangqiu Li
Format: Article
Language:English
Published: BMC 2018-08-01
Series:Molecular Cancer
Subjects:
CML
LncRNA NEAT1
SFPQ
IM
Paraspeckle
Apoptosis
Online Access:http://link.springer.com/article/10.1186/s12943-018-0884-z

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http://link.springer.com/article/10.1186/s12943-018-0884-z

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