Clinicopathologic features of TDO2 overexpression in renal cell carcinoma

Clinicopathologic features of TDO2 overexpression in renal cell carcinoma

Abstract Background Tryptophan 2,3-dioxygenase (TDO2) is the primary enzyme catabolizing tryptophan. Several lines of evidence revealed that overexpression of TDO2 is involved in anoikis resistance, spheroid formation, proliferation, and invasion and correlates with poor prognosis in some cancers. T...

Full description

Bibliographic Details
Main Authors: Quoc Thang Pham, Daiki Taniyama, Yohei Sekino, Shintaro Akabane, Takashi Babasaki, Go Kobayashi, Naoya Sakamoto, Kazuhiro Sentani, Naohide Oue, Wataru Yasui
Format: Article
Language:English
Published: BMC 2021-06-01
Series:BMC Cancer
Subjects:
Cancer stem cell
PD-L1
PTEN
Renal cell carcinoma
TDO2
Online Access:https://doi.org/10.1186/s12885-021-08477-1

Internet

https://doi.org/10.1186/s12885-021-08477-1

Similar Items